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زیست شناسی::
دیدیناز ۲
The tissues that respond earliest to the thyroid hormones are those that express high levels of deiodinase II and thus can convert Tj directly into T3 (Cai and Brown 2004).
For instance, the limb rudiments, which have high levels of both deiodinase II and TRa, can convert Xi into T3 and use it immediately through the TRa receptor.
In the tail, there is only a small amount of TRa during premetamorphosis, and deiodinase II is not detectable.
At metamorphic climax, deiodinase II is expressed and the tail begins to be resorbed.
The dorsal retina appears to be insulated from thyroid hormones by expressing deiodinase III, which degrades the T3 produced by deiodinase II.
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